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Potential Negative Effects of Sex on Women's Health

While sex offers a host of benefits such as improved immunity, stress relief, and better sleep, it can sometimes have unintended consequences for women. Here are some of the lesser-known ways in which sex can negatively affect a woman's well-being:

1. Orgasm Overload: Nervous System Overload

It turns out that an intense sexual experience, especially one that involves multiple forms of stimulation (clitoral, vaginal, and sometimes even rectal), can lead to autonomic nervous system overload. Dr. Jennifer Berman explains that intense stimulation can cause neurochemical changes that result in symptoms like dizziness, lightheadedness, and nausea. This phenomenon isn't exclusive to women—men can also experience post-orgasmic illness syndrome, which includes flu-like symptoms that can last for weeks after orgasm.

2. Depression: Post-Sex Blues

Sex is supposed to boost your mood, but for some women, it can have the opposite effect. According to a 2011 Australian study, about one-third of women report feeling depressed at least once after sex. Researchers suggest that the hormonal changes following orgasm may contribute to feelings of sadness, anxiety, or regret. Approximately 10% of women regularly feel irritable or down after lovemaking.

3. Headaches: Sex-Induced Migraines

For some individuals, sex can trigger debilitating migraines. The International Headache Society identifies two types of sex-related headaches (HSAs). Type I headaches occur during sexual excitement before orgasm, while Type II headaches are explosive, occurring during or immediately after climax. A 2012 study in the British Journal of Medical Practitioners revealed that about 1 in 100 people suffer from migraines triggered by sexual activity, with migraine sufferers being more susceptible to these headaches.

4. Allergies: Sensitivity to Condoms and Semen

Allergic reactions during or after sex can stem from several sources. Women may experience irritation from latex condoms, spermicidal jelly, or even certain lubricants. Additionally, some women may be allergic to sperm itself. The proteins in semen can sometimes trigger an immune response, causing irritation or a burning sensation. Interestingly, this reaction is often specific to the partner, and symptoms may lessen over time as the woman’s body adjusts to the partner's unique chemical makeup.

To minimize allergic reactions, it's advised to use latex-free condoms and glycerin- and paraben-free lubricants, which are less likely to cause irritation.

5. Amnesia: A Rare, Temporary Memory Loss

In rare cases, sex can lead to temporary transient global amnesia, a condition where a person suddenly loses their memory for a period of time. A case reported in The Journal of Emergency Medicine involved a 54-year-old woman who experienced complete memory loss for 24 hours, except for the fact that the amnesia began immediately following sex with her husband. While extremely rare, this case demonstrates that sex can sometimes trigger significant neurological effects.


While these effects are rare, they highlight the complex and sometimes unpredictable nature of sexual health. Women who experience any of these issues should consult with their healthcare provider to explore possible causes and treatment options.

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